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DISCOVER study presented at ICPE 2018
Diversity of sites, physicians and patients in the DISCOVER study presented at ICPE 2018.
Continuing the successful run of congress presentations of DISCOVER baseline data, Professor Wolfgang Rathmann of the DISCOVER Scientific Committee shared an insightful analysis of the diversity of the study sites, investigators and patients in a poster presented at the 34th International Conference of Pharmacoepidemiology & Therapeutic Risk Management in Prague, Czech Republic, 22–26 August 2018.
This poster reported the methodology used to select the sites and physicians invited to participate in DISCOVER, and assessed the extent to which the participating sites, physicians and patients are representative of type 2 diabetes management in each country. The invited sites were selected with the aim of being representative in terms of type of practice visited by patients, speciality of the physician, geographical and rural/urban distribution of practices, and source of funding of practices. Indeed, the combination of the relatively small proportion of rural sites and the high level of education of DISCOVER patients may result in an over-estimation of the quality of diabetes care.
Overall, ethnicity and sex distributions of participating patients were in line with data from the 2017 Atlas of the International Diabetes Federation and other sources, although the education level of participants was found to be high (78.6% of DISCOVER patients have received secondary or higher education). In some countries, rural and primary care centres were found to be under-represented due to logistical difficulties in recruiting patients from these sites, which should be considered when interpreting the results of the study.
Despite the inherent difficulties in assessing and achieving representativeness in global observational studies, the great efforts to achieve representativeness in DISCOVER have led to the inclusion of a heterogeneous patient population from clinical settings with diverse characteristics in most countries; this should ensure a high degree of external validity for the prospective study results.
Thank you to all the DISCOVER investigators for their valuable work in collecting the data that made this presentation possible and for their ongoing contributions to DISCOVER. For further updates, please keep visiting the DISCOVER website.