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Cardiovascular risk factor control in DISCOVER patients
Dr Krishna Patel presented an analysis of patterns of cardiovascular risk factor control in DISCOVER patients at the AHA QCOR Scientific Sessions,
6–7 April 2018 in Arlington, VA, USA.
Achieving control of multiple cardiovascular risk factors reduces the risk of cardiovascular events and mortality. However, the global extent of cardiovascular risk factor control in patients with type 2 diabetes is not well understood. This analysis assessed the global pattern and variability of cardiovascular risk factor control in DISCOVER patients at baseline.
A total of 15 636 DISCOVER patients from 35 countries were included in this analysis; 11.7% had atherosclerotic cardiovascular disease (ASCVD), 51.1% had hypertension and 4.2% had albuminuria. Statin treatment was prescribed in 41.7%; angiotensin-converting enzyme inhibitor or angiotensin-receptor blocker treatment was prescribed in 54.0%; and low-dose aspirin for secondary prevention was prescribed in 52.8% of patients with ASCVD. Overall, blood pressure was controlled in 67.9% of patients and 41.3% had optimal control of at least three risk factors for ASCVD. These data show that comprehensive control of ASCVD risk factors was not achieved in a large proportion (58.7%) of DISCOVER patients. There was also significant variation between countries in the achievement of optimal cardiovascular risk factor control, even after considering site and patient characteristics, suggesting that variability could be partly attributable to healthcare system differences among the countries. To improve long-term cardiovascular outcomes, better strategies are needed to provide optimal cardiovascular risk factor control in patients with type 2 diabetes.
Thank you to all the DISCOVER investigators for collecting the data that made this presentation possible. For further updates, please keep visiting the DISCOVER website.
Krishna Patel, MD, is a cardiovascular fellow at Saint Luke’s Mid America Heart Institute, Kansas City, MO, USA. She has a special interest in cardiovascular outcomes research, preventative cardiology, valvular heart disease and advanced cardiac imaging. Dr Patel is a colleague of DISCOVER Scientific Committee member Mikhail Kosiborod, MD.